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Andy Stein
May 27, 2026

Losartan – a tablet for high blood pressure 

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Losartan – a tablet for high blood pressure

It is useful in CKD patients, as it protect the kidneys – especially in people with diabetes.#


What is Losartan?

  • Losartan belongs to a group of medicines called angiotensin II receptor blockers (ARBs)
  • They are used to treat high blood pressure and protect the heart and kidneys.

How it Works

  • Losartan works by blocking the action of angiotensin II, a hormone that causes blood vessels to tighten
  • By blocking this hormone, losartan allows blood vessels to relax and widen; which lowers blood pressure and makes it easier for the heart to pump blood

Uses

Losartan is used for:

  • High blood pressure (hypertension)
  • CKD. It protect the kidneys, especially in people with diabetes
  • Reducing the risk of stroke in some patients with high blood pressure
  • Certain heart conditions, such as heart failure

Dosage

  • Losartan is taken once daily
  • Doses range from 12.5 mg to 100 mg per day, depending on the condition being treated and how the patient responds; 25 mg once day is a good starting dose

Side-effects

Most people tolerate losartan well. Possible side-effects include:

  • Dizziness or light-headedness (especially when starting treatment)
  • Low blood pressure
  • High potassium levels
  • Tiredness

Note. Rarely, it can worsen kidney function – especially in patients with CKD due to renovascular disease (RVD).


Monitoring

Doctors should regularly check:

  • Blood pressure
  • Kidney function – creatinine and GFR blood tests
  • Potassium levels

Monitoring helps ensure the medicine is working safely and effectively.

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