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Losartan – a tablet for high blood pressure
It is useful in CKD patients, as it protect the kidneys – especially in people with diabetes.#
What is Losartan?
- Losartan belongs to a group of medicines called angiotensin II receptor blockers (ARBs)
- They are used to treat high blood pressure and protect the heart and kidneys.
How it Works
- Losartan works by blocking the action of angiotensin II, a hormone that causes blood vessels to tighten
- By blocking this hormone, losartan allows blood vessels to relax and widen; which lowers blood pressure and makes it easier for the heart to pump blood
Uses
Losartan is used for:
- High blood pressure (hypertension)
- CKD. It protect the kidneys, especially in people with diabetes
- Reducing the risk of stroke in some patients with high blood pressure
- Certain heart conditions, such as heart failure
Dosage
- Losartan is taken once daily
- Doses range from 12.5 mg to 100 mg per day, depending on the condition being treated and how the patient responds; 25 mg once day is a good starting dose
Side-effects
Most people tolerate losartan well. Possible side-effects include:
- Dizziness or light-headedness (especially when starting treatment)
- Low blood pressure
- High potassium levels
- Tiredness
Note. Rarely, it can worsen kidney function – especially in patients with CKD due to renovascular disease (RVD).
Monitoring
Doctors should regularly check:
- Blood pressure
- Kidney function – creatinine and GFR blood tests
- Potassium levels
Monitoring helps ensure the medicine is working safely and effectively.