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What is a FCP (Faecal Calprotectin) Test?
- An FCP (Faecal Calprotectin) test is a non-invasive stool test that measures levels of calprotectin, a protein released into the intestines when there is inflammation.
- It is primarily used to help doctors distinguish between inflammatory bowel diseases (IBD) like Crohn’s and ulcerative colitis, and non-inflammatory conditions like irritable bowel syndrome (IBS).
Why is the test done?
Doctors typically request an FCP test if a patient is experiencing long-term gastrointestinal symptoms—such as abdominal pain, cramping, or persistent diarrhoea—and the cause is unclear.
Because symptoms of IBD and IBS are very similar, the FCP test serves as a crucial screening tool:
- Normal/Low Levels: Usually suggests a functional disorder like IBS.
- High Levels: Strongly indicates inflammation in the gut, meaning further hospital investigations (like an endoscopy or colonoscopy) may be required to get a precise diagnosis.
Common FCP Levels and Interpretation
- < 50-100 mcg/g: Normal; IBD is unlikely, often indicative of IBS.
- 100-250 mcg/g: Mildly elevated; often warrants repeat testing or clinical review.
- > 250 mcg/g: Significantly elevated; likely indicates active inflammation/IBD
Monitoring Existing Conditions
For patients who have already been diagnosed with IBD, the FCP test is highly valuable for:
- Assessing disease activity: Checking how severe the inflammation currently is.
- Monitoring treatment: Seeing if medication is successfully reducing inflammation in the bowel.
How it works
The test is very straightforward and can be completed at home:
- You collect a small stool sample in a provided container.
- You return the sample to your GP or a hospital laboratory for testing.
- It is generally advised to avoid taking Non-Steroidal Anti-Inflammatory Drugs (NSAIDs like ibuprofen or naproxen) for about 4 weeks prior to the test, as they can cause a false positive by irritating the gut.
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