How to Perform a Cranial Nerve Examination
Performing a systematic neurological examination is a sophisticated clinical skill used to localize lesions within the nervous system.
This guide focuses on the Cranial Nerve Examination, the most common neurological assessment in an OSCE setting.
Introduction: The WIPER Initial Steps
Before testing specific nerves, ensure the patient is prepared and informed:
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W – Wash: Clean your hands using the WHO 7-step technique.
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I – Introduce: State your name and role.
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P – Permission & Pain: Explain that you will be testing various senses (sight, hearing, etc.) and facial movements. Ask if the patient has any pain in the head or neck.
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E – Exposure: The patient’s face and neck should be clearly visible.
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R – (Re)position: The patient should sit comfortably on the edge of the examination couch, at eye level with you.
Part 1: General Inspection
Observe the patient from the front for subtle neurological clues:
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Asymmetry: Look for facial drooping or eye deviations.
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Ptosis: Drooping of the upper eyelid (CN III palsy or Horner’s Syndrome).
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Speech: Listen for dysarthria (slurred speech) or dysphonia.
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Involuntary Movements: Note any tremors or muscle fasciculations.
Part 2: The 12 Cranial Nerves (Step-by-Step)
I – Olfactory (Smell)
II – Optic (Vision)
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Acuity: Test using a Snellen chart (one eye at a time).
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Fields: Compare the patient’s visual fields to your own via “confrontation.”
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Reflexes: Check the Pupillary Light Reflex (Direct and Consensual).
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Accommodation: Watch the pupils constrict as the patient focuses on a near object.
III, IV, & VI – Oculomotor, Trochlear, Abducens (Eye Movement)
V – Trigeminal (Sensory & Motor)
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Sensory: Test light touch (cotton wool) in the Ophthalmic (V1), Maxillary (V2), and Mandibular (V3) distributions.
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Motor: Ask the patient to clench their teeth while you palpate the Masseter and Temporalis muscles.
VII – Facial (Motor)
VIII – Vestibulocochlear (Hearing)
IX & X – Glossopharyngeal & Vagus
XI – Accessory (Shoulder & Neck)
XII – Hypoglossal (Tongue)
Part 3: Completing the Examination
To finish your OSCE neurological assessment, state you would:
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Fundoscopy: To look for papilloedema (raised intracranial pressure).
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Peripheral Neuro Exam: Assess the upper and lower limbs (tone, power, reflexes, sensation).
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Gait Assessment: Observe the patient walking to check for ataxia.
Summary of Common Cranial Nerve Lesions
| Nerve |
Clinical Sign |
Likely Pathology |
| CN II (Optic) |
Visual field loss / Poor acuity |
Multiple Sclerosis (Optic Neuritis), Stroke |
| CN III (Oculomotor) |
Eye “Down and Out,” Dilated pupil |
Aneurysm, Diabetes (Microvascular) |
| CN VII (Facial) |
Drooping of mouth/eye |
Bell’s Palsy (LMN) or Stroke (UMN) |
| CN XII (Hypoglossal) |
Tongue deviation |
Brainstem lesion or trauma |
Video Demonstrations
For a visual guide to the 12 cranial nerves: