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CKD Made Simple: 10 Key Facts for Patients

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CKD Made Simple: 10 Key Facts for Patients


1. WHAT CKD IS

  • CKD is a long‑term reduction in kidney function (or abnormal structure with normal function)
  • Often silent in early stages
  • Usually stable for many years
  • Only 1% progress to kidney failure (CKD5, see below)

2. 5 CKD STAGES (eGFR)

Stage eGFR Meaning
CKD1–2 ≥60 ml/min Normal/near‑normal function + signs of damage
CKD3A 45–59 Mild reduction
CKD3B 30–44 Moderate reduction
CKD4 15–29 Severe reduction
CKD5 <15 Kidney failure

3. ALBUMINURIA (ACR)

Protein in urine = early sign of kidney damage.

Category ACR Meaning
A1 <3 Normal/mild
A2 3–30 Moderate
A3 >30 High
Higher CKD Stage + higher A = higher risk.

4. COMMON CAUSES

  • Diabetes
  • High blood pressure
  • Age‑related kidney blood vessel changes
  • Inflammation (glomerulonephritis, GN)
  • Blockages (prostate, stones)
  • Genetic conditions (polycystic kidneys, PKD)

5. SYMPTOMS (OFTEN LATE)

  • Tiredness
  • Swollen ankles
  • Breathlessness
  • Itching or cramps
  • Nausea
  • Night‑time urination

6. RED FLAGS — SEEK URGENT HELP

  • Chest pain
  • Severe breathlessness
  • Very little urine
  • Severe swelling
  • Palpitations or weakness (possible high potassium)

7. Treatment

TREATMENTS (GENERAL, THAT PROTECT KIDNEYS)

  • ACE inhibitors / ARBs
  • SGLT2 inhibitors
  • Statins

These reduce protein in urine, slow CKD progression, and protect the heart.

Treatment (Specific, by Cause)

  • GN → Immunosuppression
  • Obstruction → Relieve blockage
  • TIN → Stop offending drug +/- steroids
  • RVD → Cardiovascular risk management; ACE/ARBs/SGLT2is may need to be stopped
  • Diabetic nephropathy → Tight glucose control

8. LIFESTYLE TIPS

  • Keep blood pressure around 130/80
  • Avoid NSAIDs (ibuprofen, naproxen)
  • Stop smoking
  • Stay active
  • Balanced diet
  • Potassium/phosphate advice if needed

Fluid: Drink normally unless your doctor advises otherwise.


9. MONITORING

  • Blood tests (eGFR, creatinine, potassium)
  • Urine ACR
  • Blood pressure

Frequency:

  • CKD1–2: every 6–12 months
  • CKD3: every 3–6 months
  • CKD4: every 2–3 months
  • CKD5: monthly

10. WHEN TO SEE A KIDNEY SPECIALIST

  • eGFR <30 ml/min
  • Rapid decline
  • High protein in urine
  • Unclear cause
  • Difficult‑to‑control blood pressure
  • Family history of kidney disease

KEY MESSAGE

CKD is common, often silent, and usually manageable. With early detection, regular monitoring, and heart‑healthy habits, most people live well for many years.

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