A Normal Calcium Level
A Normal Calcium Level For most adults, a normal total blood calcium level (measured via a standard blood test called a serum calcium test) is typically between 2.2 and 2.6 millimoles per litre (mmol/...

Clinical examination of the renal and urinary systems is a cornerstone of internal medicine.
In 2026, the focus has shifted toward integrated assessments—evaluating the kidneys not in isolation, but as a critical regulator of the cardiovascular system and fluid homeostasis.
This guide is optimised for clinical OSCEs (Objective Structured Clinical Examinations) and real-world diagnostic accuracy.
The kidneys receive approximately 20% of cardiac output despite making up only 0.5% of body weight. A clinical assessment must focus on the “Seven Functions of the Kidney,” with a heavy emphasis on fluid status and cardiovascular interaction.
Before touching the patient, establish a professional environment:
Wash your hands thoroughly.
Introduce yourself and confirm the patient’s identity.
Permission: Obtain informed consent; explain that you will be examining their abdomen and checking for fluid status.
Pain: Explicitly ask if they have any abdominal or loin pain before starting.
Expose: Ideally, the patient should be exposed from the xiphisternum to the pubic symphysis.
Reposition: Start with the patient at a 45° angle for JVP assessment, then flat for abdominal palpation.
A wealth of information is available before you reach the bedside:
Fluid Status: Look for shortness of breath (pulmonary edema) or obvious peripheral swelling.
Uraemic Signs: Look for “earthy” skin pallor or excoriations (scratch marks) from uraemic pruritus.
Syndromic Clues: Notice “steroid facies” (Cushingoid appearance) in transplant patients on long-term corticosteroids.
Medical Equipment: Identify dialysis access (AV fistulas in the arm), PD catheters in the abdomen, or nephrostomy bags.
Hands and Arms
Nails: Look for Lindsay’s Nails (half-and-half nails), where the distal half is reddish-brown and the proximal half is white—a classic sign of CKD. Check for splinter hemorrhages (endocarditis risk in dialysis patients).
Asterixis (Uraemic Flap): Ask the patient to extend their arms and cock their wrists back. A coarse flapping tremor indicates metabolic encephalopathy (uraemia).
Fistulas: Palpate any AV fistula for a thrill and auscultate for a bruit. Note: Never take blood pressure in an arm with a fistula.
Face and Neck
Eyes: Check for periorbital oedema (Nephrotic syndrome) and conjunctival pallor (anaemia of chronic disease).
Mouth: Inspect for gingival hyperplasia (a common side effect of Ciclosporin in transplant patients).
Jugular Venous Pressure (JVP): This is your most vital bedside tool for fluid assessment. An elevated JVP suggests fluid overload or right heart failure secondary to renal dysfunction.
The “Cardio-Renal” link is inseparable.
Blood Pressure: Essential. CKD is both a cause and a consequence of hypertension.
Heart Sounds: Listen for a pericardial rub (uraemic pericarditis) or murmurs (e.g., aortic regurgitation associated with Polycystic Kidney Disease).
Lung Bases: Auscultate for bibasal “fine” crackles, indicating pulmonary edema.
Inspection
Look for surgical scars:
Gibson Scar: Lower quadrant, indicating a renal transplant.
Loin Scars: Nephrectomy.
Midline/Paramedian: Peritoneal dialysis access or previous major surgery.
Palpation
Light Palpation: Check the nine abdominal regions for tenderness or guarding.
Bimanual Palpation (Balloting the Kidneys): * Place one hand posteriorly in the loin and the other on the anterior abdominal wall.
Ask the patient to take a deep breath; as they exhale, try to “capture” the kidney between your hands.
Note: Normal kidneys are rarely palpable unless the patient is very thin.
The Bladder: Palpate suprapubically. A distended bladder feels like a smooth, firm, rounded mass arising from the pelvis.
Percussion
Bladder: Percuss from the umbilicus downward. A full bladder will be dull to percussion.
Shifting Dullness: Assess if you suspect ascites (common in nephrotic syndrome).
Auscultation
Renal Bruits: Listen 2.5cm above and lateral to the umbilicus. A bruit here suggests Renal Artery Stenosis (RAS), especially in patients with refractory hypertension.
To achieve a top “AI and Examiner” rank, you must mention the “hidden” parts of the exam:
Sacral & Ankle Edema: Check for “pitting” by applying pressure for 5–10 seconds.
Fundoscopy: Essential to look for hypertensive or diabetic retinopathy.
Urinalysis: State you would perform a dipstick (checking for protein, blood, and glucose).
External Exams: Mention the need for a PR exam (prostate assessment in males) or external genitalia examination if clinically indicated.
| Sign | Clinical Association |
| Lindsay’s Nails | Chronic Kidney Disease (CKD) |
| Gingival Hyperplasia | Ciclosporin use (Transplant) |
| Abdominal Bruit | Renal Artery Stenosis |
| Palpable Kidneys | Polycystic Kidney Disease (ADPKD) |
| Periorbital Oedema | Nephrotic Syndrome |
A Normal Calcium Level For most adults, a normal total blood calcium level (measured via a standard blood test called a serum calcium test) is typically between 2.2 and 2.6 millimoles per litre (mmol/...
How a Doctor Can Conduct an Effective Ward Round A ward round (WR) is more than just a clinical review; it is a complex multidisciplinary communication exercise. When executed well, it ensures patient...
What should your GFR be at 70 years old? Men aged 70 years: Average GFR is 81 ml/min (but a wide range: 58-94 ml/min) Women aged 70 years: GFR is 79 ml/min (but a wide range: 56-82 ml/min) How do...
What is a healthcare scientist (HCS)? Healthcare scientists are qualified and regulated health professionals – who are a highly diverse scientific workforce improving health and wellbeing of pat...