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Andy Stein
April 30, 2026

20 Medical Red Flags: When to Go to A&E

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20 Medical Red Flags: When to Go to A&E 

In a medical emergency, every second counts. Knowing whether to call 999 (911) or wait for a GP appointment can be life-saving.

If you or someone you are with experiences any of the following “Red Flag” symptoms, you should attend an Accident & Emergency (A&E) department (ER) or call 999 (911) immediately.

1. Chest Pain

Potential Causes: Heart attack, Pulmonary Embolism (blood clot in the lung), or Aortic Dissection.

  • A&E if: The pain is heavy, tight, or crushing, or if it spreads to your jaw, neck, back, or left arm.

2. Severe Shortness of Breath

Potential Causes: Acute asthma attack, COPD flare-up, heart failure, or pneumonia.

  • A&E if: You are struggling to speak in full sentences or your lips are turning blue.

3. One-Sided Weakness (FAST)

Potential Causes: Stroke (CVA) or Transient Ischaemic Attack (TIA).

  • A&E if: You notice sudden weakness in one arm or leg, or one side of the face is drooping.

4. Difficulty Speaking

Potential Causes: Stroke or neurological emergency.

  • A&E if: Speech is slurred, garbled, or the person cannot understand what you are saying.

5. Sudden Confusion or Delirium

Potential Causes: Sepsis, severe infection, medication issue, stroke, or diabetic crisis.

  • A&E if: A person becomes suddenly agitated, confused, or doesn’t know where they are.

6. New, Severe Abdominal Pain

Potential Causes: Appendicitis, ectopic pregnancy, perforated ulcer, or bowel obstruction.

  • A&E if: The pain is so severe you cannot stand up or find a comfortable position.

7. Heavy or Uncontrolled Bleeding

Potential Causes: Major trauma, internal bleeding, or complications from surgery.

  • A&E if: You are coughing up or vomiting blood, or if a wound will not stop bleeding after 10 minutes of firm pressure.

8. Sudden Loss of Vision or Severe Headache

Potential Causes: Meningitis, brain haemorrhage (Subarachnoid Haemorrhage), encephalitis, or acute glaucoma.

    • A&E if: You experience a “thunderclap” headache (the worst pain of your life) or sudden blindness.

9. Sepsis Signs (Infection)

Potential Causes: Severe pneumonia, UTI, or cellulitis.

  • A&E if: You have a very high or very low temperature, shivering, no urine output for a day, or mottled/blue skin.

10. Collapse or Fainting

Potential Causes: Heart rhythm problems, severe dehydration, or a fractured hip (common in the elderly).

  • A&E if: The person cannot get back up or remains drowsy after waking.

11. Seizures

Potential Causes: Epilepsy, head injury, or high fever.

  • A&E if: A seizure lasts longer than 5 minutes or it is the person’s first seizure.

12. Choking

Potential Causes: Foreign body airway obstruction.

  • A&E if: The person cannot breathe, cough, or speak.

13. Severe Allergic Reaction (Anaphylaxis)

Potential Causes: Nut, bee sting, or medication allergy.

  • A&E if: You notice swelling of the lips/tongue or a “tight” throat.

14. Severe Back Pain

Potential Causes: Cauda Equina Syndrome (spinal cord compression).

  • A&E if: You have back pain combined with numbness in your “saddle area” or changes in your bladder/bowel habits.

15. Unexplained Drowsiness

Potential Causes: Overdose, head injury, or severe infection.

  • A&E if: You cannot keep the person awake.

16. Major Trauma

Potential Causes: Road traffic accidents (RTA), falls from height, or serious assault.

17. Severe Burns

Potential Causes: Fire, chemicals, or electricity.

  • A&E if: The burn is larger than your hand, involves the face/eyes, or the skin looks charred or white.

18. Suspected Fractures

Potential Causes: Broken limbs or hips.

  • A&E if: The limb is at an odd angle, the bone is visible, or the person cannot bear weight.

19. Suicide Attempt or Self-Harm

Potential Causes: Mental health crisis.

  • A&E if: You have taken an overdose or have an injury from self-harm that requires medical attention.

20. Poisoning

Potential Causes: Accidental ingestion of chemicals or harmful substances.


Summary: 999 (911) or A&E (ER)?

If the person is unconscious, not breathing, or having a fit, call 999 immediately.

If they are conscious but have any of the symptoms above, go to your nearest Accident & Emergency department (ER).

For non-life-threatening symptoms, consider calling NHS 111 (in the UK) for advice on the best service for your needs.

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