Almost all drugs can affect the kidneys in some adverse way. But these 10 drugs are known to damage kidneys quite often.
Aminoglycosides (e.g. gentamicin) and beta-lactams (cephalosporins, penicillins).
Angiotensin-converting enzyme inhibitors (ACE inhibitors, e.g. ramipril), angiotensin receptor blockers (ARBs, e.g. losartan).
[“Yes, it is confusing that such drugs are potentially harmful to the kidneys and protective of them, at the same time.” MyHSN Ed”]
A form of chemotherapy (and other chemotherapeutic agents).
Can cause acute kidney injury (AKI) due to contrast-induced nephropathy (CIN) – used in x-rays such as CTs and angiograms.
All diuretics including thiazide (e.g. bendroflumethazide), loop (furosemide and bumetanide) and potassium-sparing (spironolactone).
Such as aristolochic acid. One of the authors of MyHSN has seen chinese herbal medicines cause temporary or permanent dialysis.
These are important immunosuppressants, ironically used to prevent kidney transplant rejection. Therefore doctors try to use the lowest effective dose by measuring blood levels.
Such as lansoprazole, pantoprazole, and omeprazole.
The above list is by no means a comprehensive list of medications that can cause kidney damage. You are at higher risk of drug-induced kidney damage if you are over 60 years, have underlying CKD, or comorbidities such as diabetes.
If this is the case, you should talk to your doctor before starting any new medication that can potentially cause kidney damage.
Stopping or using the minimum dose of these tablets can help prevent CKD.
Note. But please do not stop the tablets above if you think they are becoming nephrotoxic (kidney damaging). Speak to your doctor urgently.
We have described 10 drugs that can affect your kidneys. We hope it has been helpful.
